NMNAT2 is a key protein required for axon integrity whose rapid depletion following axon injury triggers Wallerian degeneration. The molecular mechanism controlling NMNAT2 turnover in neurons has not ...

Effective axon regeneration is critical for restoring nerve function in patients with axon injury-related neurological ...

After an injury, there is often damage to the nerves. These nerves usually regenerate using innate processes. Researchers from Gutenberg University Mainz (JGU) and at the Swiss University of Fribourg ...

The regeneration of damaged neurons has been the ultimate goal for a large portion of neuroscience research. Understanding the underlying mechanisms that control neuronal growth is key to developing ...

New research reveals that parts of the neuron are far more complex than once thought. As far as cells go, neurons are pretty weird. Most other cells come in spherical blob-like shapes with a central ...

Schwann cells are a type of glial cells of the peripheral nervous system that help form the myelin sheath around the nerve fibers. Schwann cells are derived from the neural crest and play crucial ...

This is a preview. Log in through your library . Abstract Here, we use a mouse model (DBA/2J) to readdress the location of insult(s) to retinal ganglion cells (RGCs) in glaucoma. We localize an early ...

Researchers have discovered a new way to prevent brain nerve cells from deteriorating after injury, which also revealed a potential mechanistic link between TBI and AD. Their discovery also yielded a ...

Researchers from the F.M. Kirby Neurobiology Center in the US have discovered a new approach to restore myelin sheaths, the fatty substance that surrounds nerve cells. The findings may be able to aid ...

Brains run on constant streams of chatter. The roughly 85 billion nerve cells in the human brain converse by sending messages via molecules called neurotransmitters. These chemical conversations allow ...