This review illustrates how the nuclear phosphoinositide-p53 signalosome integrates lipid signaling and p53 function to regulate cancer cell motility. The figure contrasts the tumor-suppressive ...
In this review, the authors present recent findings that uncover a previously unappreciated nuclear signaling hub: the PIPn-p53 signalosome. This complex not only modulates AKT activation within the ...
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Genetic study links vitamin B1 metabolism to gut motility and IBS risk
By Dr. Priyom Bose, Ph.D. By analyzing bowel movement frequency in more than 268,000 people, researchers uncover how thiamine-processing genes shape gut motility, link constipation and diarrhea to ...
A key pressure-sensing protein involved in intestinal movement and inflammation regulation has been identified. Researchers from Harvard Medical School (MA, USA) and the Icahn School of Medicine at ...
PHILADELPHIA — Cancer cells’ quick moves may make them skilled escape artists. Some cancer cells appear to wriggle away from immune cells trying to gobble them up. These evasive maneuvers — caught on ...
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