The coagulation cascade is a finely balanced system essential for maintaining haemostasis, yet its disruption can lead to either a propensity for bleeding or an increased risk of clot formation.

Hemophilia A and B involve deficiencies in coagulation factors VIII and IX, with traditional treatments requiring frequent infusions. Nonfactor therapies, including Hemlibra and rebalancing agents, ...

Protein S activity is a test to judge your risk of blood clots. Blood clots that form in the veins are dangerous. Protein S is a substance that controls the blood clotting mechanism and prevents ...

A recent study provides new insights into the mechanisms of coagulation in persons with haemophilia A, the most common form of haemophilia. The research team was able to show that saliva contains ...

Megakaryocytes, which are derived from hematopoietic stem cell precursors in bone marrow, form and release platelets; these circulate in the blood for 8 to 10 days before they are removed by hepatic ...

Coagulation studies help you understand blood disorders, so you can pursue treatment options to improve your blood’s ability to form clots. Blood coagulation, or blood clotting, is a process in which ...

Coagulation disorders refer to conditions that affect how the body controls blood clotting. This can mean the body forms too many or too few blood clots. Coagulation disorders are usually due to a ...

Researchers at Oregon Health & Science University have uncovered how a molecule found on certain bacteria may drive blood clotting in sepsis, a life-threatening condition that causes about 8 million ...

In the early days of the New York Covid-19 outbreak, as March turned to April, hematologist Jeffrey Laurence was called to consult on the case of a 32-year-old bodybuilder. Nurses had noticed an odd ...

For more than 40 years as a researcher and clinician, Joseph Broderick has actively contributed to improvements in stroke care, occupying a front row seat to seismic innovations: the clinical trials ...

The coagulation factor XI (FXI) from the liver acts as an endocrine molecule in the heart, protecting it from heart failure. Scientists at the University of California, Los Angeles (UCLA) found that ...