SportsLine's model simulated Indianapolis vs. San Francisco on 'MNF' 10,000 times and reveals its NFL picks today

Virginia plays Duke for the second time this season in a battle with high stakes and an ACC Championship on the line. Who will prevail in this rematch? Let's take a look at some bold predictions for the game on Saturday.

Oklahoma football eyes its first national title since the 2000 season. Alabama stands in the way, leading to these predictions.

Preview the Week 17 matchup between the Denver Broncos and Kansas City Chiefs with predictions, odds, over/under, spread, betting lines and more.

The Minnesota Vikings face the Detroit Lions in Week 17 of the NFL season on Christmas Day at U.S. Bank Stadium.

The Vikings topped the Lions 27-24 from Ford Field in Detroit on Nov. 2 in the season's first meeting. Though Lions quarterback Jared Goff passed for 284 yards and two scores, Detroit fumbled once, had a field goal blocked,

The Broncos and Chiefs will author the latest chapter of their AFC West rivalry in a Week 17 clash on Christmas night.