MIT engineers have challenged a core idea in biology by showing that epigenetic memory is not simply binary. Their research reveals cells don’t just lock genes in an “on” or “off” state. Instead, they ...
A new CRISPR breakthrough shows scientists can turn genes back on without cutting DNA, by removing chemical tags that act ...
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Jumping genes reshape cancer genomes through 3D chromatin interactions
Scientists at St. Jude Children's Research Hospital have revealed previously unappreciated roles for the retrotransposon LINE-1 in shaping the cancer genome structure and regulation.
Cells are constantly on the move, whether in a developing embryo or metastatic cancer. But how do cells adapt to new environments they encounter? Traditionally, scientists have believed that cells ...
“Our findings suggest a role for NSD2 in maintaining MM cell identity, with potential implications for future therapeutic strategies based on targeting of NSD2.” “Our findings suggest a role for NSD2 ...
Researchers uncover key mechanisms in gene regulation that may lead to better design of RNA-based medicines. RNA-based medicines are one of the most promising ways to fight human disease, as ...
Scientists at St. Jude Children's Research Hospital and Northwestern University identified a previously unknown treatment opportunity for sickle cell disease and β-thalassemia. The discovery, ...
Hair loss and graying, the earliest visible hallmarks of skin aging, result from the functional decline of hair follicle stem ...
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