ascopubs.org

Relationship of induction of apoptosis by caffeine and the cAMP, PTEN, Akt-inhibition signaling pathway in sarcoma cells.

Criteria defining the duration of chemoreduction with focal treatment in retinoblastoma: A retrospective analysis. Background: Caffeine is a radio- and chemo-sensitizing agent acting by inhibiting ATM ...
JSTOR Daily

Induction of Primordial Germ Cells from Murine Epiblasts by Synergistic Action of BMP4 and BMP8B Signaling Pathways

Extraembryonic ectoderm-derived factors instruct the pluripotent epiblast cells to develop toward a restricted primordial germ cell (PGC) fate during murine gastrulation. Genes encoding Bmp4 of the ...
Healio

High-dose buprenorphine safe, well-tolerated in opioid users

Please provide your email address to receive an email when new articles are posted on . Patients with untreated opioid use disorder responded well to a high-dose induction of buprenorphine in the ED, ...
Forbes

Major Protease Of SARS-CoV-2 Acts To Suppress Innate Immunity

This is part nineteen of a series, “How SARS-CoV-2 Delays, Evades, and Suppresses the Immune System.” In October 2020, researchers discovered that the SARS-CoV-2 nonstructural protein 5 (NSP5), like ...
ascopubs.org

Induction of endothelial proliferation and angiogenesis through activating the ERK1/2/EGF pathway mediate by CXC chemokine receptor 2 by chemokine (C-X-C motif) ligand 1.

Efficacy of cabazitaxel and its relationship with predictors of poor response to second hormonal therapies (2d HT) in metastatic castration-resistant prostate cancer (mCRPC). This is an ASCO Meeting ...
JSTOR Daily

SAMHD1 suppresses innate immune responses to viral infections and inflammatory stimuli by inhibiting the NF-κB and interferon pathways

Sterile alpha motif and HD-domain–containing protein 1 (SAMHD1) blocks replication of retroviruses and certain DNA viruses by reducing the intracellular dNTP pool. SAMHD1 has been suggested to ...