In addition to a greater risk for serious infection, patients with atopic dermatitis initiating JAK inhibitors vs Th2 cytokine inhibitors had a greater risk of Candida infections and a slightly ...

Editor’s note: This is an automatically generated transcript. Please notify [email protected] if there are concerns regarding accuracy of the transcription. Certainly we've learned a lot about JAK ...

We were unable to process your request. Please try again later. If you continue to have this issue please contact [email protected]. MIAMI BEACH, Fla. — Janus kinase inhibitors are an ...

A systematic review reports that monoclonal antibodies and JAK inhibitors can be effective in the treatment and clearance of ...

Researchers conducted a multicentric real-world retrospective study of 241 patients across 11 dermatologic centres in the Czech Republic between January 2022 and September 2024. Participants with ...

Over the last decade, research and development of Janus kinase (JAK) inhibitors have exploded. Three years ago, JAK inhibitors were on the cusp of being available for dermatologic indications. In this ...

Alopecia areata is a chronic autoimmune disorder causing non-scarring hair loss due to immune system attacks on hair follicles. Breakdown of immune privilege in hair follicles leads to infiltration by ...

The 2023 Fall Clinical Dermatology conference will take place in Las Vegas and be livestreamed from October 19 to 22; topics of interest to be covered include atopic dermatitis (AD), Janus kinase (JAK ...

Over the past decade, patients with moderate to severe rheumatoid arthritis who have not had success with established treatments have been able to turn to a new class of drugs called Janus kinase (JAK ...

Newer oral medications for rheumatoid arthritis (RA) do work quite well in the "real world," despite some doubts that they would, according to a new study. The study, of 622 adults with RA, found that ...

Approved JAK inhibitors such as ruxolitinib and fedratinib target the JH1 kinase domain, offering symptomatic relief but lacking selectivity for the mutant form. This non-selective inhibition disrupts ...