One of the most detailed 3D maps of how the human chromosomes are organized and folded within a cell's nucleus is published ...

Synthetic hydrogel-based assay to study 3D confined cell migration. Credit: Science Advances (2024). DOI: 10.1126/sciadv.adm9195 Eukaryotic cells—that is, cells with a nucleus—possess an astounding ...

Could scientists detect neurodegenerative diseases like Alzheimer's and ALS years or decades before these disorders manifest outward signs? What could researchers learn by following hundreds of ...

The notion that the interior of the nucleus is compartmentalized goes back to the discovery of the nucleolus in the 1830s. Today, we know that numerous, discrete domains related to gene expression ...

A lattice model with side chains was used to investigate protein folding with computer simulations. In this model, we rigorously demonstrate the existence of a specific folding nucleus. This nucleus ...

From reproductive rights to climate change to Big Tech, The Independent is on the ground when the story is developing. Whether it's investigating the financials of Elon Musk's pro-Trump PAC or ...