This is a preview. Log in through your library . Abstract Freeze-fracture studies have shown a network of intramembrane fibrils in the tight junctions of epithelia. A direct correlation between the ...

With the increasing exploration of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) – the causative pathogen of coronavirus disease 2019 (COVID-19) pandemic – it has become clear that ...

Gap junctions consist of arrays of intercellular channels between adjacent cells that permit the exchange of ions and small molecules. Here we report the crystal structure of the gap junction channel ...

They seal epithelial cells and, under certain conditions, allow the passage of ions and water: Tight junctions form a paracellular barrier in tissues and their dysfunction is associated with diseases.

COLD SPRING HARBOR, N.Y. (May 11, 2010) --Cell-cell junctions are multi-molecular complexes that link neighboring cells. They help maintain tissue integrity, act as barriers to permeability, and allow ...

As a human embryo grows, a set of molecules directs cells as they multiply and take on specific identities and spatial positions within the embryo. In one crucial step known as gastrulation, these ...

Gastrulation lays the groundwork for the whole human body's development. Researchers have discovered a way to replicate a simplified version of this fundamental process in a dish by beginning with a ...