Corticospinal motor neurons are the motor system’s foreman, according to Hande Özdinler of the Northwestern University Feinberg School of Medicine in Chicago. They listen to what the brain wants, and ...
Cognitive impairment is a common feature of ALS: frontotemporal dementia and ALS constitute the ends of a spectrum reflecting different manifestations of the same pathogenic mechanism Upper and lower ...
The classification of ALS can vary depending on the criteria used. The traditional definitions of ALS subgroups are based on the extent of involvement of upper and lower motor neurons, although other ...
It is easy to confuse one motor neuron disease for another: amyotrophic lateral sclerosis, primary lateral sclerosis, and lower motor neuron disease can all mimic each other. But each has a slightly ...
A diagnosis of amyotrophic lateral sclerosis can be overlooked by clinicians unfamiliar with the various signs of the disease. ALS is purely a motor neuron disease; sensory neurons are not affected. 4 ...
Motor neuron disease (MND) is a progressive condition that occurs when certain nerve cells degenerate and die. There are two types of motor neuron cells. The upper motor neuron begins in the brain and ...
Current clinical assessments evaluating selective voluntary motor control are measured on an ordinal scale. We combined the Selective Control of the Upper Extremity Scale (SCUES) with surface ...
Areflexic, or flaccid, bladder and bowels occur when the spinal cord injury is low enough to damage the cauda equina and alpha motor neurons. It also occurs in all spinal cord injury patients during ...
Primary lateral sclerosis (PLS) and amyotrophic lateral sclerosis (ALS) are neurodegenerative diseases. PLS typically develops slowly, while ALS rapidly affects mobility and can become fatal.
Brian Wainger, MD, PhD, of the Healey Center for ALS at Massachusetts General Hospital (MGH) presented initial, top-level results of a recently completed phase 2 clinical trial of ezogabine (also ...
Primary lateral sclerosis (PLS) is a rare neurological disorder that affects the motor neurons in the brain and spinal cord, which control movement. It is a form of motor neuron disease (MND). PLS ...
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