Lysosomes are membrane-bound organelles whose acidic lumen (pH 4.5–5.0) is required for degradation. This luminal acidity is ...

Scientists at Sanford Burnham Prebys have found a new way to kill pancreatic cancer cells by disrupting their pH equilibrium. The study, published in Cancer Discovery, reports how depleting an ion ...

Colorectal cancer, the abnormal growth of cancerous cells in the large intestine or the rectum, is one of the most common ...

There are many differences that help us distinguish healthy cells from cancerous cells—from shape to growth to signaling. Another way is by their pH. The pH in a cancerous cell is not the same as the ...

The inside of a living cell is a surprising patchwork of environments. For example, pH levels can vary dramatically in different organelles, despite them being just a couple hundred nanometers apart.

Acidity (pH) in cells of baker's yeast regulate the synthesis of cell membranes by controlling the production of enzymes that synthesize membranes. The elucidated mechanism is so simple and universal ...

In a first for the condensate field, researchers have figured out how nucleolar sub-structures are assembled. This organization gives rise to unique pH profiles within nucleoli, which they measured ...