In life-threatening sepsis, the same signalling pathway that protects young mice from succumbing to organ dysfunction exacerbates damage and lethality in older animals. Defects in elastin trigger ...

This study provides new insights into the role of endoglin (ENG) as a co-receptor in endothelial cells and addresses a gap-in-knowledge on how ENG could be involved in both TGF-β and BMP9 signalling.