Macrolide antibiotics like azithromycin rely on a complex ring structure that’s powerful but notoriously hard to control.  Researchers have uncovered how bacterial enzymes shape this ring during the ...

Complex sugar-protein molecules that sense external messages to help a cell grow or respond to its environment can now be ...

Itaconate, an endogenous mitochondrial metabolite produced by the enzyme aconitate decarboxylase 1 (ACOD1), has emerged as a central regulator of ...

Researchers developed LS-170, an inhibitor of the ATAC complex, which suppressed oncogene expression and reduced tumor growth ...

Researchers have identified OTULIN, an immune-regulating enzyme, as a key trigger of tau buildup in the brain. When OTULIN ...

A team led by UT Southwestern Medical Center researchers has uncovered a molecular pathway that links obesity to widespread ...

A research team has uncovered and reconstructed the complete biosynthetic pathway of polyphyllin II—a potent anticancer ...

The strategy, known as synthetic biology, is gaining momentum globally as a conservation tool and human health solution, ...

The interdisciplinary collaboration was led by Professor Xiang David LI (HKU Chemistry), together with Professor Weiping WANG (HKU Pharmacology and Pharmacy), Researcher Xin LI (Shenzhen Bay ...

How weight loss and diet changes show up in lab results Weight loss creates measurable improvements in lab work that doctors track regularly throughout your journey.

No gene acts alone: interacting variants and protein partnerships can worsen, mask or even rescue disease risk, demanding ...