Macrolides are an important class of antibiotics that includes drugs such as azithromycin and erythromycin, which are widely ...

Macrolide antibiotics like azithromycin rely on a complex ring structure that’s powerful but notoriously hard to control.

Complex sugar-protein molecules that sense external messages to help a cell grow or respond to its environment can now be ...

A research team has made a breakthrough in epigenetic drug discovery. The researchers have successfully developed a ...

The interdisciplinary collaboration was led by Professor Xiang David LI (HKU Chemistry), together with Professor Weiping WANG (HKU Pharmacology and Pharmacy), Researcher Xin LI (Shenzhen Bay ...

Itaconate, an endogenous mitochondrial metabolite produced by the enzyme aconitate decarboxylase 1 (ACOD1), has emerged as a central regulator of ...