Fatty acid oxidation (FAO) disorders comprise a heterogeneous group of inborn errors of metabolism that impair the mitochondrial capacity to convert fatty acids into energy. These inherited conditions ...
Scientists at the Institute of Molecular Biology and Biotechnology (IMBB-FORTH) and the University of Crete, together with ...
The raw material for de novo fatty acid synthesis is acetyl-CoA, which can be obtained via the citrate shuttle pathway or from acetic acid. ACC and FASN catalyze the conversion of acetyl-CoA into ...
Cancer immunotherapy is a type of cancer treatment that harnesses the immune system to fight cancer cells. The treatment ...
The role of FAO in cancer. FAO provides three essential substances for tumor metabolism, namely acetyl-CoA, NADPH, and ATP. Genes & Diseases publishes rigorously peer-reviewed and high quality ...
The results from the clinical trials of POM3, both alone and with statin co-therapy, are concordant with expectations based on kinetic studies. The proposed mechanisms for the effects of POM3 on the ...
The tumor microenvironment (TME) is a metabolically dynamic niche where cancer cells and immune cells interact to influence tumor progression and immune ...
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