Christian McCaffrey had 107 yards from scrimmage in his season debut. The 49ers are a different team when McCaffrey is on the ...

San Francisco leaders and community members came together Sunday to continue to fight for safer streets on World Day of ...

San Francisco’s Muni launched its first-ever online merchandise store yesterday, releasing over 30 products with the Muni ...

Forward, a San Francisco health technology company once valued at $1 billion, is shutting down after failing to popularize ...

Down the stretch against the Seattle Seahawks, San Francisco 49ers star pass rusher Nick Bosa was on the sideline. In the ...

The San Francisco Giants head into the offseason having missed the postseason in seven of the last eight years.

The San Francisco 49ers have had to deal with a significant number of injuries to their star players this season, and after ...

New photos show the sickening moment a California man launched a savage assault on a female Safeway employee in San Francisco ...

A judge has temporarily ordered Oakland International Airport in California to stop using the name "San Francisco Bay Oakland ...

The 49ers won the first meeting in Seattle, 36-24, for their sixth straight victory against the Seahawks, counting their ...

San Francisco Mayor-elect Daniel Lurie discussed defeating his more progressive opponent Mayor London Breed on CNN’s “Erin ...