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  1. MTHFR Gene Variant and Folic Acid Facts | Folic Acid | CDC

    May 27, 2025 · You may have heard that if you have an MTHFR variant, you should avoid folic acid and should take other types of folate, such as 5-MTHF. However, this is not true.

  2. Methylenetetrahydrofolate reductase - Wikipedia

    Methylenetetrahydrofolate reductase (MTHFR) is the rate-limiting enzyme in the methyl cycle, and it is encoded by the MTHFR gene. [5] Methylenetetrahydrofolate reductase catalyzes the …

  3. MTHFR Gene Mutation: Symptoms, Testing, and Treatments

    Feb 25, 2025 · MTHFR is a gene everyone has. Some mutations of the MTHFR gene may be associated with health problems and complications in pregnancy. Learn about determining …

  4. MTHFR mutation: Symptoms, testing, and treatment

    Aug 21, 2025 · Methylenetetrahydrofolate reductase (MTHFR) is an enzyme that breaks down the amino acid homocysteine. If the MTHFR gene that codes for this enzyme mutates, it may …

  5. MTHFR Gene Mutations: What You Need to Know - WebMD

    MTHFR gene mutation affects folate metabolism, linked to higher risk of cardiovascular issues, blood clots, and certain birth defects. It influences methylation and homocysteine levels.

  6. MTHFR is a gene that makes an enzyme called MethyleneTetraHydroFolate Reductase. This enzyme works with a B-vitamin called folate. Together, MTHFR and folate help to reduce the …

  7. MTHFR gene: MedlinePlus Genetics

    The MTHFR gene provides instructions for making an enzyme called methylenetetrahydrofolate reductase. Learn about this gene and related health conditions.

  8. MTHFR Gene Mutations and Disease - Verywell Health

    Nov 10, 2025 · Methylenetetrahydrofolate reductase (MTHFR) is an enzyme produced by the MTHFR gene. MTHFR interacts with folate (vitamin B9) to break down homocysteine so that it …

  9. MTHFR Gene: Key Facts, Symptoms, and Treatment Options

    The MTHFR gene is essential for processing folate in the body. Mutations in this gene can lead to elevated homocysteine levels, which are linked to various health issues, including …

  10. MTHFR Gene Mutation: Deficiency, Symptoms, Testing, Treatments

    Sep 9, 2024 · Read on to learn more about the MTHFR gene mutation symptoms, testing, and treatments. MTHFR gene mutations can cause elevation of blood homocysteine levels, some …